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pentobarbital will minimize the extent or influence of methadone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.pentobarbital will lower the extent or result of atogepant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Advisable atogepant dosage with concomitant use of r